Pentobarbital will decrease the extent or influence of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Potent or average CYP3A4 inducers may increase amount of diazepam elimination; consequently, efficacy of diazepam could be lessened. pentobarbital will lower the extent or effect of lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 https://gloriaa963mpr4.ltfblog.com/profile